Friday, September 21, 2018

Regency period medicine and the inspiration behind Florian - the physician in The Illegitimate Duke





One of my favorite things about being an author, aside from sharing my stories with readers, is all the wonderful information I find while doing research. Writing The Illegitimate Duke allowed me to dive back into Regency medicine, an area that first caught my interest seven years ago when I started work on There’s Something About Lady Mary. What intrigues me just as much now as it did back then, is discovering how advanced some physicians and surgeons were in the past. They weren’t all the blood-letting quacks so often depicted in the movies. For instance, I bet it would surprise you to know that the first successful heart surgery on record, was performed by the Spanish surgeon, Francisco Romero, in 1801! Granted, he ‘only’ worked on the lining of the heart in order to drain excess fluid, but he did this twice without either patient dying. And don’t forget that this was done at a time before anesthesia, which is really quite amazing. Unfortunately, finding information on Francisco Romero wasn’t easy. It required a bit of digging and eventually I just stumbled upon him by chance. If you do a search for ‘history of heart surgery’ or ‘first heart surgery’ etc. other more recent surgeons are credited, which in my opinion is rather unjust.

Delayed acceptance of discovery happens in all areas of science, of course, but it always happens in the field of medicine with great poignancy, since there the human costs of dropping the technological ball are usually great. – Alcor. Life Extension Foundation

Similarly, Charles Kite and William Buchan were medical pioneers who ought to be household names. Instead, other people are more famously known for discoveries and claims these men made long before anyone else. I bet it would surprise you to know that the first cardiac defibrillation was given to a three year old girl on July 16th 1774, long before Jean-Louis Prevost and Frederic Batelli demonstrated the use of defibrillation in 1899. When Catharine Sophie Greenhill fell out of a first floor window, an apothecary pronounced her dead. Thankfully, a neighbor named Squires, an amateur scientist, arrived on the scene twenty minutes later with an electrostatic generator and proceeded to pass electricity through her body. History records that after giving her several shocks to the chest, her pulse reappeared and she began breathing again. Eventually, after a short time in coma, she recovered fully.
This incident is remarkable and this is where Charles Kite comes in, because he took note. As a member of the Humane Society (still in existence today and originally named The Society for the Recovery of Persons Apparently Drowned), he not only advocated the resuscitation of people in cardiac arrest by using bellows as well as oral and nasal intubation, but also developed his own electrostatic revivifying machine. This used Leyden jar capacitors in a similar way to the DC counter shock of the modern cardiac defibrillator, which makes you stop and think, doesn’t it? I mean, we’re still talking late 18th Century here since Kite received a silver medal for his work in 1788.



In The Illegitimate Duke, the hero, Florian Lowell, is a very progressive man of medicine who has traveled the world and likes to keep up to date with new discoveries. Through him and his conversations with the heroine, Juliette Matthews, it is my hope that Charles Kite will be brought to people’s attention and remembered for his extraordinary contribution to both science and medicine.
The same can be said about William Buchan. I have used his book, Domestic Medicine, as the foundation for Florian’s knowledge about hygiene. He even lends the book to Juliette and advises her to read it. This is because it really aggravates me when the wrong person is acknowledged for an achievement. While the Hungarian physician, Ignaz Philipp SemIgnaz (1818-1865), did find the connection between the handling of corpses and puerperal fever in childbirth, he is not the first person to discover the significance of hand washing, even though his finds in this area did result in greater attention to cleanliness in operating rooms.
Because here’s the problem with that theory: William Buchan wrote about the importance of hand washing in Domestic Medicine, first published in 1772, where he says: 

Were every person, for example, after handling a dead body, visiting the sick, etc, to wash before he went into company, or sat down to meat, he would run less hazard either of catching the infection himself, or communicating it to others.

Buchanan also mentions the importance of cleanliness aboard a ship where escaping an epidemic would be difficult. In this context, he advises that if infectious diseases were to break out, cleanliness is the most likely way to prevent it from spreading. This includes the washing of all clothing and bedding used by the sick as well as fumigation with brimstone or the like.
In The Illegitimate Duke, Florian applies these methods during a typhus outbreak. He uses tar water instead of brimstone, however, and cleans the quarantine ship with a solution of lime, as implemented by the Edinburgh Infirmary and advised by practitioners of the Royal Army and Navy during the early 19th Century. Furthermore, inspiration for the treatment of typhus was found in the Edinburgh Infirmary’s insistence that patients be stripped of their clothing, given haircuts to remove lice (which would have been helpful since typhus was spread by lice, though this wasn’t known until Charles Nicolle made the connection in 1903) given a bath and in some cases rubbed with mercurial ointment.
Florian also uses morphine, a narcotic that wasn’t commercially available in 1821 when the story takes place, even though it had been produced in Germany by pharmacist Friedrich Sertürner in 1804. I like to think that Florian corresponded with Sertürner who happily supplied him with morphine after Florian carried out his own tests. This attention to detail and willingness to stay apprised of medical advancements is what makes Florian such a wonderful physician and hero.
When asked how he came by his profession, he responds:

“Saving lives is a never- ending struggle against the evils of the world. The things I have seen have changed me in ways I am not always fond of. When I began my apprenticeship, I was sixteen years old and used to a life of leisure and luxury. Seeing a boy my own age lose a limb that first day was shocking. I confess I fled the operating room to cast up my accounts.”
“And the boy?”
“He died three days later from infection.” Florian’s voice was strained with emotion. “I made it my purpose then and there to discover the best methods of medical treatment and surgery. Forced to complete my apprenticeship in order to be admitted into Oxford, I dedicated my free time to reading medical texts and interviewing not only other physicians, but anyone I could find who had traveled abroad and born witness to successful surgeries.”

Since Florian had the funds to attend university and I don’t go into detail, this doesn’t really convey how easy it was to gain a medical education and start your own practice prior to 1815. Apprenticeships for physicians, apothecaries and surgeons were extremely popular. No examination was required at the end, which lead to a huge imbalance in student competence, depending on who the teacher had been.
Like Florian, many aspiring physicians did attend university since this added an element of prestige to their profession. But obtaining a degree did not require the sort of hands on experience one might expect. It focused mostly on writings of physicians from classical times such as Hippocrates and Galen and on the student’s ability to defend two theses before the Professor of Medicine in Latin. Shockingly, however, it was quite acceptable for the student to pay someone to do this for him.



Some of this leniency changed after 1815, at least for the apothecaries who were now obligated to adhere to the Apothecaries Act. Enforced by the Society of Apothecaries and requiring qualifying examinations, its main features were:
       The Society of Apothecaries became the main examining body for entry into general medical practice
       A five year apprenticeship was compulsory
       The holder of the Licence of the Society of Apothecaries (LSA) must be willing to dispense physicians' prescriptions
       The LSA was compulsory for all who dispensed
It seems that because of the lack of regulations during most of the nineteenth century, ridding the medical community of quacks and ensuring high levels of skill, was an uphill battle. Even so, there were some remarkable physicians and surgeons who were truly dedicated to their work and to their patients, such as Charles Kite and Franciso Romero. These are the men on whom Florian is based – on the men who saw medicine as a vocation instead of simply a way in which to make a living.

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